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The change to agar was a marked improvement. The jelly is so effective that it is still an invariable ingredient in what is known today as the “Koch’s plating technique” or the “culture plating method.” As Koch himself noted in 1909: “These new methods proved so helpful…that one could regard them as the keys for the further investigation of microorganisms…Discoveries fell into our laps like ripe fruits.”
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Екатерина Ештокина
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在医学上，青春期并不是一个模糊的概念。自20世纪中期以来，儿科和内分泌学界主要通过几类指标来判断青春期的启动时间：女孩乳房发育的起始（thelarche）、阴毛出现，以及第一次月经（初潮，menarche）。这些体征被系统地纳入性成熟评定分期体系（ Tanner ），并长期作为国际通用的临床评估工具。